'Genetics of Depression' update

January 24, 2019



One of the first initiatives that the GHFC took an active interest in was an Australian based study into the links between genetics and depression. Following is an update to the GHFC from Professor Nick Martin, Senior Scientist with QIMR Berghofer Medical Research Institute:

Dear Charles,

Just a brief update on how this project is progressing.

Data collection is still ongoing, with over 16,000 DNA samples collected from participants so far. Over 2,000 samples were collected in the past 12 months, which is a great effort!

DNA from the 14,000 samples collected last year have been extracted and transferred to a specialised laboratory for genotyping (turning DNA into genetic code). This is a long process and we expect data to be ready for cleaning and analysis in the first half of 2019.
While this is all happening we will be preparing the next batch (n=2000+) of samples for extraction and genotyping, set for the end of the year.

This data and sample collection phase of the study will continue till the end of this year. Once we have a final dataset (most likely 2020) we can then start the analysis into the genetics of depression and how genes affect anti-depressant medications.

We will keep you updated on the outcomes of this analysis.

Once again, we are very grateful for your support, and encourage you to spread the word about our ground breaking study.

Yours sincerely,

Professor Nick Martin

Senior Scientist  |  QIMR Berghofer Medical Research Institute

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